MARS MAGLINE Reagents

MARS MAG LINE is a family of reagents that use anti-PE Magnetic Nanobeads to capture PE-labeled subpopulations of white blood cells. The reagents have been shown to enable fast and easy isolation of T cells, B cells, Monocytes, Neutrophiles, Rare Cells, MRDs, DTCs, and many others. Developed exclusively for the MARS instrument MAG modules, together […]

Enhanced Rare Cell Sorting Capability Enabled by MARS and WOLF 

MARS acoustic technology utilizes active-microfluidics acoustics for the separation of sample particles without labeling, based only on the difference in their physical parameters. The isolated cells are ready for negative MARS MAG selection, where cells bound to magnetic beads are captured in flow channels, without the need for dedicated columns. Combining the two technologies, MARS enables […]

High purity and recovery Positive Selection of CD34+ cells from Whole Blood

CD34+ cell isolation from whole blood is usually performed with RBC lysis or a density gradient separation method, typically using Ficoll – based protocols. This methodology is very time and labor-intensive and leads to high cell loss. Our No-Lyse-No-Wash (NLNW) protocol is fast and cost-effective. The MARS Bar system together with MARS MAG LINE of […]

Fast and Gentle Cell Isolation from Human Lung Tumor Biopsy Sample

MARS technology utilizes active-microfluidics acoustics for the separation of tissue sample particles without labeling, based only on the difference in their physical parameters. The system allows for the efficient removal of lysed cell debris, dead cells, and other small particles. The isolated cells are ready for single-cell phenotypic and genomic analysis as well as expansion. MARS […]

Fast and Gentle Neutrophil Isolation with MARS

Neutrophils are very sensitive to vigorous mixing and pipetting, which often result in cell activation. Neutrophil isolation from whole blood is usually performed with RBC lysis or density gradient separation method, typically using Percoll-based or Ficoll – based protocols. MARS CS workflow for gentle Neutrophil selection provides high purity and yield with: over 87% Neutrophil purity with gentle RBC lysis and our proprietary […]

High Performance Large Scale T Cell Isolation with MARS 

Efficient T cell isolation with high recovery and high purity is important for academic and clinical research. Using our newly developed MARS system (multi-physics automated reconfigurable separation) we demonstrate an automated process to isolate T cells within a short time. With MARS Bar, we achieved greater than 95% purity of T cells isolated from a […]

Fast and Efficient TIL Cells Isolation from a Lung Tissue Biopsy Sample

Efficient TIL cell isolation from biopsy samples is important for academic and clinical research. Using our newly developed MARS system (multi-physics automated reconfigurable separation) we demonstrated a label-free automated process to isolate TIL cells directly from a dissociated tissue sample. With MARS Separation, we separated tumor cells as well as dead cells and debris from TIL […]

High Speed, High Recovery of Immune Cells Prepared From Whole Blood Using the MARS Sample Preparation System

Blood immune cell flow cytometry analysis is a standard practice in both research and clinical labs. The immune cell preparation from whole blood samples normally requires multiple manual cell washing steps with centrifugation.The process can be tedious, labor intensive, time consuming, and inconsistent. We developed a new sample preparation MARS system, using an acoustic active-microfluidic […]

Rare Cancer Cell Isolation From Whole Blood Using the MARS Cell Separation System

Circulating tumor cells (CTCs) are cancer cells shed from tumors and circulate in the bloodstream. These cells are considered to be a biomarker which potentially has high value in cancer diagnosis and cancer drug development. However, because of the extremely low frequency of CTC in peripheral blood, which is typically as low as less than […]

Applied Cells Inc. Enters Collaborative Research Agreement for the Development of Rare Cell Isolation in Minimum Residual Disease

Detection of Disseminating Tumor Cells (DTCs) holds promise for the early detection of potential relapse.  The presence of bone marrow DTCs correlate with increased relapse risk, decreasing overall survival. Applied Cells, a commercial provider of cell preparation and isolation solutions for tumor biology research, today announced that it will further its research collaboration on rare […]