Introducing the MARS® Bar system, a breakthrough in in-flow Immunomagnetic cell isolation technology. Our systems offer positive and negative cell selection workflows, ensuring the separation of target cell subpopulations with exceptional purity, recovery, and viability.
MARS® is an open platform, accommodating various magnetic bead types, including those directly coated with antibodies tailored to your specific cell surface markers or molecules. Experience the simplicity and efficiency of cell isolation with MARS® – where innovation meets practicality, advancing research possibilities.
Three independent modules ensure the functionality of a system, even in the unlikely event of a module clogging.
Our matrix-free magnetic column reduces dead volume and cell trapping for more efficient positive or negative cell enrichment and higher recovery.
In-line pressure sensors
1 of 4Module progress LED bar enabling remote monitoring of separation process
2 of 4Magnetic separation channel
3 of 4Multiple size tube holders
4 of 4MARS Bars systems demonstrated a consistent and simple scaling-up capacity.
Equipped with a Bag arm and pre-programmed for a repeated releasing cycles, provides the capacity to process billions of cells in a single closed system operation.
MARS® BAR Flex | MARS® BAR | |
---|---|---|
SAMPLE | ||
Magnetic Cell labelling | ✓ | ✓ |
Containment | 5mL, 15mL, 50mL, tubes | Bags |
Sample processing |
1 sample each module Max 3 samples in parallel |
1 sample by 3 parallel channels |
Sample types | ||
Whole blood | ✓ | ✓ |
Apheresis | ✓ | ✓ |
Leukopaks | ✓ | ✓ |
Frozen PBMC's | ✓ | ✓ |
Bone marrow | ✓ | ✓ |
Dissociated Tissue | ✓ | |
REAGENTS & CONSUMABLES | ||
Isolation buffer | MARS® MAG buffer | |
Isolation reagents | ||
MARS MAG lines (RUO) | ✓ | |
MARS Ingenuity Line (RUO, GMP) | ✓ | ✓ |
Fluidics |
Open end tubing sets Cleaning and sterilizartion protocols |
Closed tubing set (Gamma radiated) |
CELL ISOLATION | ||
Positive isolation | ||
Direct from Whole | ✓ | ✓ |
Blood & Leukopak | ✓ | ✓ |
Depletion | ✓ | ✓ |
Positive & negative tubing sets | Same (program enabled change) | |
OPERATIONS | ||
Speed Column-free |
Protocol dependent; 0.5-6 ml/min | |
MARS® MAG in-flow technology | ✓ | ✓ |
Separation channels | Flex-BIBO scalable | |
Redundancy | 3x Modules | |
Time to assemble tubing set | <5min* | <15min* |
Time to initiate isolation | <2min | < 8min |
Typical time to process 1e9 cells | <20min (3 modules, single batch) | <30min (25e6/mL) |
Capacity | 0.5 - 45 mL per module |
20mL - 1L Expandable > 1L |
Max total cells processable | No practical limit | |
Batched isolation | ✓ | ✓ |
Operation in bio-safety hood | ✓ | N/A |
Additional configuration | Serial program | N/A |
SOFTWARE | ||
Pre programmed protocols | ✓ | ✓ |
Adjustable & lockable parameters | ✓ | ✓ |
Tiered user rights | ✓ | ✓ |
Logged UI events | ✓ | ✓ |
Encrypted logs | ✓ | ✓ |
INSTRUMENT | ||
Dimensions |
20.5" W 16.5" D x 19,75" H 52cm W x 41 cm D x 50 cm H |
20.5" W x 16.5" D x 28" H 52cm W x 52cm D x 74cm H |
Weight | 62 lb/ 28kg | 59 lb/ 27 kg |
* With standard training |
Download Technical
Specification pdf
MARS® Bar platform supports your cell development process from end to end, from small-scale optimization, through easy upscaling, to cell manufacturing.
Choose one of MARS gentle, centrifuge-free and Ficoll-free workflows for immunoselection of TIL, T Cells, NK cells Neutrophils or Stem cells.
Easy and fast debris removal to feed genomic platforms with enriched cells from samples including Whole Blood, tumor, PMBC, solid tissue and many others.
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