With parallel processing of up to 3 samples, bags compatible holding arm, and the sample flow rate of 1 mL/min, MARS Bar and MARS Bar Flex modules allow for hands-off analysis of a large variety of volumes and samples in a short time.
Three independent modules ensure the functionality of a system, even in the unlikely event of a module clogging.
Our matrix-free magnetic column reduces dead volume and cell trapping for more efficient positive or negative cell enrichment and higher recovery.
In-line pressure sensors
1 of 4Module progress LED bar enabling remote monitoring of separation process
2 of 4Magnetic separation channel
3 of 4Multiple size tube holders
4 of 4MARS Bars systems demonstrated a consistent and simple scaling-up capacity.
Equipped with a Bag arm and pre-programmed for a repeated releasing cycles, provides the capacity to process billions of cells in a single closed system operation.
MARS® BAR Flex | MARS® BAR | |
---|---|---|
SAMPLE | ||
Magnetic Cell labelling | ✓ | ✓ |
Containment | 5mL, 15mL, 50mL, tubes | Bags |
Sample processing |
1 sample each module Max 3 samples in parallel |
1 sample by 3 parallel channels |
Sample types | ||
Whole blood | ✓ | ✓ |
Apheresis | ✓ | ✓ |
Leukopaks | ✓ | ✓ |
Frozen PBMC's | ✓ | ✓ |
Bone marrow | ✓ | |
Dissociated Tissue | ✓ | |
REAGENTS & CONSUMABLES | ||
Isolation buffer | MARS® MAG buffer | |
Isolation reagents | ||
MARS MAG lines (RUO) | ✓ | |
MARS Ingenuity Line (RUO, GMP) | ✓ | ✓ |
Fluidics |
Open end tubing sets Cleaning and sterilizartion protocols |
Closed tubing set (Gamma radiated) |
CELL ISOLATION | ||
Positive isolation | ||
Direct from Whole | ✓ | ✓ |
Blood & Leukopak | ✓ | ✓ |
Negative depletion | ✓ | ✓ |
Positive & negative tubing sets | Same (program enabled change) | |
OPERATIONS | ||
Speed Column-free |
Protocol dependent; 0.5-6 ml/min | |
MARS® MAG in-flow technology | ✓ | ✓ |
Separation channels | Flex-BIBO scalable | |
Redundancy | 3x Modules | |
Time to assemble tubing set | <5min* | <15min* |
Time to initiate isolation | <2min | < 8min |
Typical time to process 1e9 cells | <20min (3 modules, single batch) | <30min (25e6/mL) |
Capacity | 0.5 - 45 mL per module |
20mL - 1L Expandable > 1L |
Max total cells processable | No practical limit | |
Batched isolation | ✓ | ✓ |
Operation in bio-safety hood | ✓ | N/A |
Additional configuration | Sequential process** | N/A |
SOFTWARE | ||
Pre programmed protocols | ✓ | ✓ |
Adjustable & lockable parameters | ✓ | ✓ |
Tiered user rights | ✓ | ✓ |
Logged UI events | ✓ | ✓ |
Encrypted logs | ✓ | ✓ |
INSTRUMENT | ||
Dimensions |
20.5" W 16.5" D x 19,75" H 52cm W x 41 cm D x 50 cm H |
20.5" W x 16.5" D x 28" H 52cm W x 52cm D x 74cm H |
Weight | 62 lb/ 28kg | 59 lb/ 27 kg |
* With standard training ** Customizable |
Download Technical
Specification pdf
MARS® Bar platform supports your cell development process from end to end, from small-scale optimization, through easy upscaling, to cell manufacturing.
Choose one of MARS gentle, centrifuge-free and Ficoll-free workflows for immunoselection of TIL, T Cells, NK cells Neutrophils or Stem cells.
Easy and fast debris removal to feed genomic platforms with enriched cells from samples including Whole Blood, tumor, PMBC, solid tissue and many others.
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