MARS active-microfluidics acoustics allow for label-free immune cells separation from lysed cell debris, dead cells, and other small particles. The acoustic force within MARS® CPC (Cell Processing Chip) separates particles based on differences in their physical parameters (size, etc.) with high speed. The CPC is tunable to preferably enrich desired cells. Isolated cells are ready for single-cell phenotypic and genomic analysis as well as expansion.
MARS immuno-magnetic separation modules separate cells bound to magnetic beads from cells unbound to magnetic beads in flow channels, without the need for dedicated columns. No matrix means that the dead volume is reduced, and a minimal number of cells are trapped in the system, leading to unprecedented recovery.
Built-in release cycle programmed to cyclically release cells bound to magnetic beads to the positive fraction offers an unlimited cell capacity and prevents clogging.