Redefining CD138+ Plasma Cell Isolation for Multiple Myeloma Clinical Research
CD138+ Plasma Cell Enrichment directly from Bone Marrow
CD138 expression is a crucial marker in diagnosing plasma cell tumors and Multiple Myeloma cells. Traditionally, the evaluation of plasma cells from bone marrow involves a time-consuming and labor-intensive density gradient separation method using ficoll. However, this method leads to the loss of antigens, including CD138, from the plasma cell surface, necessitating immediate staining and […]
从全血中直接分离高纯度 CD138+浆细胞
骨髓浆细胞（BM）的细胞遗传学特异性特征是诊断和监测多发性骨髓瘤（MM）的一种常见的基因检测方法。多发性骨髓瘤患者的浆细 胞比例从1%到100%不等。尽管有些研究显示外周血中循环浆细胞（CPCs）比在骨髓中的风险低100倍以上，但由于其样本采集的侵入性 较低，它们的存在仍被认为是多发性骨髓瘤患者预后的一个重要标志。然而，耗时的样品制备步骤和在此过程中大量的细胞损失仍是一 个重大的挑战。MARS®平台通过一种简单的方法从外周血中分离CD138+浆细胞，而不需要RBC裂解和密度梯度离心。
High Purity Plasma CD138+ Cell Isolation straight from Whole Blood
Characterization of Plasma Cells in Bone Marrow (BM) for cytogenetic abnormalities is a common genetic test to diagnose and monitor multiple myeloma (MM). Plasma cells in MM patients vary in proportion from <1% up to 100%. Even though Circulating Plasma Cells (CPCs) burden in peripheral blood is reported to be >100-fold lower than in BM, their presence […]
A New Approach for High Recovery and Purity Isolation of Plasma Cells from Whole Blood
Characterization of Plasma Cells in Bone Marrow for different cytogenetic abnormalities is a common genetic test to diagnose and monitor cell malignant disease such as multiple myeloma (MM). Plasma cells in MM patients varied in proportion from <1% up to 100%. For the less invasive sample collection, circulating plasma cells (CPCs) in peripheral blood have emerged as an important […]