Mouse Brain Tumor Cells Pre-Enrichment for Increased FACS Throughput
The new MARS acoustic technology utilizes active-microfluidics acoustics for the separation of single cells or nuclei without labeling, based only on the difference in their physical parameters. The cells are isolated with high recovery and ready for flow sorting, single-cell genomics and many other applications.
Singulator® and MARS®: Efficient Nuclei Isolation from a Variety of Tissue Samples
MARS acoustic technology utilizes active-microfluidics acoustics for the separation of single cells or nuclei without labeling, based only on the difference in their physical parameters. The cells are isolated with high recovery and ready for single-cell genomics. The Singulator System automates the processing of solid tissue samples into suspensions of single cells or nuclei with high […]
A Novel Platform Providing Automated, Consistent and Gentle Cell Isolation from Tissues for Downstream Applications
INTRODUCTION Tumor-infiltrating lymphocytes (TILs) are lymphocytic cells that have invaded the tumor tissue. Adoptive cell therapy (ACT) of TILs is a strategy to modify the immune system to recognize tumor cells and carry out an anti-tumor effector function. Today, TIL therapies consist of ex vivo expansion of TIL from resected tumor material and adoptive transfer […]
Acoustic cell separation platform for efficient preparation of single cell/nuclei suspension from complex samples for genomics analysis
INTRODUCTION The scale and capabilities of single-cell RNA-sequencing methods have expanded rapidly in recent years, enabling major discoveries and large-scale cell mapping efforts. Sample types go beyond simple cultured cell line cells and blood cells to all types of tissues: fresh or frozen. In certain cell types, single nuclei isolation is much easier than single […]
Gentle Nuclei Isolation from Tissue Samples
Fast and Gentle Cell Isolation from Human Lung Tumor Biopsy Sample
MARS technology utilizes active-microfluidics acoustics for the separation of tissue sample particles without labeling, based only on the difference in their physical parameters. The system allows for the efficient removal of lysed cell debris, dead cells, and other small particles. The isolated cells are ready for single-cell phenotypic and genomic analysis as well as expansion. MARS […]