Target Cell Isolation
Flexible workflows for high cell purity and recovery
Applications
Improve Performance & Consistency in Your Cell selection Workflows. From rare cells to T-cells, the MARS system can isolate target cells with high recovery, high purity, and high reproducibility. Our unique approach enables research and cost-effective clinical solutions. MARS platform offers easy workflow to enrich cells in complex samples therefore enables breakthrough in detection limit in various cancer types.
Less manipulation means higher recovery and higher viability.
CAR-T Therapy
In the past twenty years, T cell-based immunotherapies have greatly revolutionized the field of cancer treatment and enormous efforts have been devoted to developing new drugs as well as improving the efficiency of manufacturing processes. At AC, we provide researchers with technological solutions promising flexibility and scalability.
γδ T cells, the minor subsets of T cells hold promise for adoptive immunotherapy through their unique reactivity to bacteria, viruses, and tumours. However, because they constitute a small fraction (1–5%) of the peripheral T-cell pool, the isolation of γδ T cells requires a highly efficient, yet gentle isolation workflow.
CAR-NK Therapy
NK cells have gained significant attention in the field of cancer immunotherapy. Obtaining a large quantity of NK cells requires a democratized cell isolation solution for both pre-clinical and clinical applications. We enable large-scale magnetic CD56+ cell isolation technology for the separation of Apheresis, Leukopaks, Whole Blood or Bone Marrow cell products.
Stem Cell Therapy
Multipotent haematopoietic stem cell (HSC) therapy is a popular technique with a range of promising health benefits. One of the recognized challenges is the ability to quickly obtain a sufficient number of desired cell types for transplantation, with high purity. We address it through an easy method to isolate CD34+ cells from fresh or mobilized blood without RBC lysis and density gradient centrifugation.
Two powerful technologies
MARS Acoustic Wash
Acoustic debris removal is a label-free technique that utilizes acoustic waves to manipulate and separate cells based on their physical properties, including size and density.
Unlike conventional approaches, acoustic debris removal offers ease of operation, gentle processing and high purity of separated cells. It is also excellent for handling delicate and fragile cell types and single nuclei in preparation for single-cell genomics experiments.
MARS Magnetic Separation
Our proprietary in-flow technology of column-free immunomagnetic separation provides a highly flexible, scalable, and cost-effective solution for cell separation. MARS magnetic separation eliminates the need for a matrix columns, reducing cell loss and delivering high cell purity and excellent recoveries for various samples.
The MARS® Mag modules are supported by optimized protocols for automated cell enrichment or depletion, ensuring assay reproducibility. The technology also boasts unlimited capacity, as the captured cells are eluted cyclically at pre-defined time intervals until all cells are separated.
MARS® system
Acoustic debris removal and In-flow Immunomagnetic cell isolation are two technologies for positive and negative cell selection workflows, that enable the separation of specific target cell subpopulations with high purity, recovery and viability. MARS® is an open platform, which means that is supports a range of magnetic bead types, including beads directly coated with antibodies against specific cell surface markers or a molecule, to best match your application and the target cell type you plan to isolate.
Discover MARS® Technology
Watch our webinar introducing MARS® platform and new approaches to sample preparation, that are gentle, efficient, and rapid solutions for easy sample preparation and cell manufacturing.
Three reagent lines
MARS® MAG Line
A line of reagents with anti-PE Magnetic nanobeads used for capturing PE-labeled subpopulations of White Blood cells. Use for isolating cell like: T cells, B cells, Monocytes, Neutrophiles, Rare Cells, MRDs, DTCs, and others.
MARS® MAG Premium Line
Launched in collaboration with STEMCELL Technologies, designed for exceptional purity and ease of use for isolating various cell types, such as granulocytes, NK cells, and plasma cells.
MARS® Ingenuity Line
A line offering a seamless transition from small, lab bench scale workflow to manufacturing-scale Cell Therapy development with reproducible performance. Includes RUO and GMP reagents for use in Cell Therapy Development projects.
Explore other MARS® Platform Applications
Cell Therapy
Explore other MARS® Platform Applications
