Applied Cells Opens the CellQuest Grant to Advance Multiple Myeloma Research
We’re delighted to share the launch of the CellQuest Grant for clinical research scientists specializing in multiple myeloma and cell therapy development. This initiative, open until mid-November 2023, grants the winning researcher access to the MARS® Bar cell separation system for six months. Additionally, the package comes complete with essential reagents, training, and expert assistance. […]
CD34+ Cell Isolation from Cord Blood MNC
CD34+ cells offer valuable insights into hematopoiesis, hematological disorders, and regenerative medicine. They have potential in cancer therapies, autoimmune diseases, and genetic disorders. Isolating CD34+ cells from Cord Blood Mononuclear Cells (MNC) is crucial for research in hematopoietic stem cell biology and therapeutic advancements. MARS® Platform ensures the enrichment of CD34+ cells, enhancing purity, viability, […]
CD138+ Plasma Cell Enrichment directly from Bone Marrow
CD138 expression is a crucial marker in diagnosing plasma cell tumors and Multiple Myeloma cells. Traditionally, the evaluation of plasma cells from bone marrow involves a time-consuming and labor-intensive density gradient separation method using ficoll. However, this method leads to the loss of antigens, including CD138, from the plasma cell surface, necessitating immediate staining and […]
Applied Cells Joins MassBio
We are thrilled to share the news that Applied Cells has officially become a member of MassBio! MassBio, the Massachusetts Biotechnology Council, is driven by a powerful mission: to propel Massachusetts to the forefront of life sciences leadership, fostering industry growth, enhancing the healthcare system, and ultimately improving the lives of patients. Serving as the […]
ASGCT 2023: Simple magnetic cell separation for both autologous and allogenic cell therapy development
INTRODUCTION Adoptive cell therapy has proven clinical efficacy in many cancer types and the success has driven more development of new drugs. However, on the manufacturing side, current process using conventional tools is complicated and results in suboptimal purity and yield sometimes. All those shortcomings may contribute to the high cost of the cell products […]
Simple magnetic cell separation enabled by an automated, closed system for both autologous and allogenic cell therapy development
INTRODUCTION Adoptive cell therapy has demonstrated effective clinical results in various types of cancer, leading to increased efforts in developing new drugs. However, the current manufacturing process using conventional tools is complex and often yields impure products, contributing to the high cost of cell therapy and limiting patient access. Both industry and academic cell therapy […]
通过无柱免疫细胞磁分选工作流程从 TCR α/ß+中分离TCR γ/δ+
近年来 T 细胞受体 (TCR) 细胞疗法因其为癌症和感染性疾病提供一系列可能性的治疗而获得广泛关注。由于γδ T细胞被视为对癌症免疫治疗颇有潜力的区域细胞，基于γδ T细胞的新型免疫疗法正在被大力开发。尽管TCR疗法在研发、生产及临床应用等领域已经取得重大进展，但 TCR细胞疗法的开发在功效及安全性方面仍然面临很多挑战。 MARS® 平台为优化和扩大 γδ T细胞的研发和生产提供了一种简单而又全新的方法和工具，可以帮助TCR 疗法最大化的发挥临床潜力。
TCR γ/δ+ separation from TCR α/ß+ with MARS® Bar
In recent years T cell receptor (TCR) cell therapy has gained popularity due to a range of possible treatments for cancer and some infectious diseases it could provide. Since γδ T-cells constitute promising effector cell compartments for cancer immunotherapy, novel γδ T-cell-based immunotherapies are being developed. Although advancements in TCR engineering, manufacturing, and clinical applications have led to […]
Quality Assistant/Assistant Quality Engineer
We are searching for a Quality Assistant who will assist the Quality Manager with the creation, maintenance, and improvement of an ISO 13485 Quality System and other regulatory affairs. Level of Experience: Entry-Level Responsibilities Assist with document control processes and procedures. Assist with internal and external auditing processes. Support the preparations for regulatory submissions for […]
MARS® MAG Premium Line
MARS® MAG Premium Line is a family of cell separation reagent kits launched in collaboration with STEMCELL Technologies. These reagents have been shown to enable fast and easy isolation of many cell types, including granulocytes, NK cells, and plasma cells. With protocols optimized for the MARS instruments, the kits provide an integrated cell isolation solution. This is especially […]