MARS® Ingenuity™ Line of Reagents brochure
MARS® Ingenuity™ Reagent kits offer comprehensive solutions for the advancement of global cell therapy research, development and manufacturing. Designed with both Research Use Only (RUO) and GMP-grade reagents, these kits provide a fast and straightforward approach to cell isolation, supporting a wide range of therapies including CAR-T, immune cell-based therapies, stem cell-based therapies, and cancer […]
T cell Isolation using CD3/CD28 microbeads
The success of CAR T cell therapy in blood cancers highlights the need to optimize manufacturing for wider access, and efficient T cell isolation is crucial, impacting therapy effectiveness. Demand for better isolation methods is rising. CD3/CD28 microbeads are gaining attention for simplifying processes and enhancing workflow. They activate a wide range of T cells, […]
AACR 2024: A Novel Automated Platform for Rapid Manufacturing of CAR-T Cells
Autologous cell therapy using T cells that are genetically modified to express a chimeric antigen receptor (CAR) has yielded durable responses in patients with cancers. However, globally only a small fraction of eligible patients are privileged to receive the treatment. High cost and long manufacturing time contribute to the key limitations prohibiting a broad adoption […]
Column-Free CD14+ Monocyte Isolation using 50nm Superparamagentic Beads on MARS® Bar
Dendritic cells are professional antigen-presenting cells and they play a key role in the regulation of immune responses. Dendritic cells are widely used as vaccines and drugs for cancer treatment in a large number of trials. Macrophages are essential innate immune cells and when activated, macrophages can mediate the phagocytosis of dangerous cells or materials […]
Column-Free T cell Isolation using 50nm Superparamagentic Beads on MARS® Bar
The therapeutic efficacy of CAR T cells has been firmly established in hematologic malignancies and the key is to develop a low-cost manufacturing process to enable the wide adoption of the therapy. T cell isolation being upstream process for CAR T cell manufacturing has significant impact on the quality of the T cells and the […]
Applied Cells announces first recipients of CellQuest grant at 65th ASH Annual Meeting and Exposition
Applied Cells had the pleasure of attending the 65th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, CA, on December 9-12. The team had a wonderful time engaging in insightful discussions on the future of hematology with visitors and taking part in the event’s comprehensive program. This also provided Applied Cells […]
Applied Cells will showcase cutting-edge MARS® Bar technology at the 65th ASH Annual Meeting and Exposition
We are thrilled to be attending the 65th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, CA, from December 9-12. Our team looks forward to the event’s comprehensive program of signature lectures, insightful scientific workshops and dedicated special interest sessions, as well as discussing the latest developments in the field of […]
Improving cell isolation for advanced Stem Cell therapy development
Redefining CD138+ Plasma Cell Isolation for Multiple Myeloma Clinical Research
“Manufacturing Chemist” Features Our CEO, Dr. Yuchen Zhou, on Pioneering Stem Cell Separation
In a recent article published by ‘Manufacturing Chemist‘, our CEO, Dr. Yuchen Zhou, provides a comprehensive insight into the obstacles impacting stem cell therapy research. A significant issue lies in the cell separation stage, often leading to lengthy preparation times and substantial cell loss. Dr. Zhou articulates the ambition of Applied Cells Inc.: to address […]