Applied Cells had the pleasure of attending the 65th American Society of Hematology (ASH) Annual Meeting and Exposition in San Diego, CA, on December 9-12. The team had a wonderful time engaging in insightful discussions on the future of hematology with visitors and taking part in the event’s comprehensive program. This also provided Applied Cells with the opportunity to showcase the MARS® Bar demonstrating and discussing the instruments’ capabilities for enriching target cells with high purity, reproducibility and recovery for various research applications.
The highlight of the event for the team was announcing the three recipients of the company’s CellQuest grant, all of whom are undertaking exceptional multiple myeloma or cell therapy research projects. The chosen researchers will enjoy a six-month placement of the MARS Bar instrument, together with cell isolation reagents and consumables, comprehensive training, application development support, and ongoing assistance from a dedicated application scientist.
Introducing the winners of CellQuest 2023 Grant
Dr Doriana Gramegna, coordinator of the Multiple Myeloma Translational Research Unit at Istituto Tumori Giovanni Paolo II in Bari, Italy
Dr Doriana Gramegna and team will use access to the MARS Bar to launch a project Deciphering the myeloma microenvironment for personalized bispecific antibody therapy. The study aims to address current treatment challenges through decoding the tumor microenvironment and presenting a personalized interpretation of transcriptomic data. The project has the potential to unveil new molecular targets for therapy, reshaping precision medicine for multiple myeloma.
Dr Sabina Ševčíková, Associate Professor, Babak Myeloma Group at Masaryk University in Brno, Czech Republic
The group will use the MARS in its project on Unravelling molecular markers in multiple myeloma relapse. This study will investigate the molecular mechanisms driving multiple myeloma relapse, focusing on non-coding RNA molecules and the endoplasmic reticulum stress response, with the aim of informing the development of targeted clinical strategies, improving patient outcomes and enhancing the quality of life of those living with multiple myeloma.
Dr Vanessa Desantis, Research Fellow in the Department of Biomedical Sciences and Human Oncology, University of Bari, Italy
Dr Vanessa Desantis’ group will use the grant to run their project entitled Optimising the crosstalk between the immune microenvironment and multiple myeloma. The team will explore the intricate relationship between the immune microenvironment and multiple myeloma plasma cells to unravel the molecular mechanisms behind the disease progression and drug resistance. Dr Desantis and her colleagues envision that the results will help to pave the way towards personalized treatments that will ultimately improve patient outcomes.
Exploring new frontiers in hematology
It was an enriching experience for the Applied Cells’ team to be a part of the 65th ASH Annual Meeting and Exposition, and we are grateful for the opportunity to contribute to global advancements in hematology research with our CellQuest grant. For those who couldn’t join us at the event, we invite you to explore our website to learn more about the MARS instruments and stay updated on our latest innovations.