Multiphysics innovation for high speed, high recovery, and high viability automated cell separation

INTRODUCTION Tumor biology, immunology, and immune-oncology from multi-omics at the single cell level have witnessed an unprecedented acceleration in recent years, with a major contribution of such speedup from new technologies and products bursting into the market. New technological solutions also contributed deterministically to the promise of cell-based therapy. However, conventional cell separation tools, such […]

Novel Multiphysics Cell Separation Platforms for Cell Therapy Development

INTRODUCTION In the past twenty years, cell therapy has made great success in treating patients and enormous efforts have been devoted to developing new drugs as well as improving the efficiency of manufacturing processes. New technological solutions with flexibility and scalability are desired to support the promise of cell-based therapy. MARS Cell Separation Platforms incorporate […]

NK cell isolation with MARS® Platform

Over the last years, NK cells have gained significant attention in the field of cancer immunotherapy and many efforts are emerging for developing and engineering NK cell-based cancer immunotherapy. Obtaining a large quantity of NK cells requires a democratized cell isolation solution for both pre-clinical and clinical applications. The new MARS Bar system enables a […]

Fast and Gentle Cell Isolation from Human Lung Tumor Biopsy Sample

MARS technology utilizes active-microfluidics acoustics for the separation of tissue sample particles without labeling, based only on the difference in their physical parameters. The system allows for the efficient removal of lysed cell debris, dead cells, and other small particles. The isolated cells are ready for single-cell phenotypic and genomic analysis as well as expansion. MARS […]

High Performance Large Scale T Cell Isolation with MARS 

Efficient T cell isolation with high recovery and high purity is important for academic and clinical research. Using our newly developed MARS system (multi-physics automated reconfigurable separation) we demonstrate an automated process to isolate T cells within a short time. With MARS Bar, we achieved greater than 95% purity of T cells isolated from a […]

Fast and Efficient TIL Cells Isolation from a Lung Tissue Biopsy Sample

Efficient TIL cell isolation from biopsy samples is important for academic and clinical research. Using our newly developed MARS system (multi-physics automated reconfigurable separation) we demonstrated a label-free automated process to isolate TIL cells directly from a dissociated tissue sample. With MARS Separation, we separated tumor cells as well as dead cells and debris from TIL […]